Mirena IUD: Implanted in the womb it releases small amounts of hormones and lasts up to 5 years. Since taking estrogen has been linked to increased risk of stroke and some birth control pills contain estrogen, many healthcare providers are reluctant to prescribe birth control pills with high levels of estrogen to women 35 and older. The belief was that these pills raise the risk of cancer, stroke, and heart disease as women grow older. Yes, hormonal birth control methods, such as the pill, are safe for most women. Related Questions If you’re over 35 and a smoker, you shouldn’t use the combination pill or any other kind of birth control that contains the hormone estrogen. The lower-dose pills now in use have no such problems, according to recent studies.